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The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases
Patients with primary immunodeficiency (PID) provide rare opportunities to study the impact of specific gene mutations on the regulation of human B cell tolerance. Alterations in B cell receptor and Toll-like receptor signaling pathways result in a defective central checkpoint and a failure to count...
Tallennettuna:
| Päätekijä: | |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925509/ https://ncbi.nlm.nih.gov/pubmed/22236425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2011.06347.x |
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