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Changes in the three-dimensional structure of concanavalin A upon demetallization

When the Mn(2+) and Ca(2+) ions normally present in concanavalin A are removed, the protein becomes incapable of binding saccharides. To explore the structural differences between the native and demetallized forms and their effects on the saccharide-binding properties of the protein, we have refined...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Reeke, George N., Becker, Joseph W., Edelman, Gerald M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1978
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392537/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/276870/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.5.2286
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