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Changes in the three-dimensional structure of concanavalin A upon demetallization

When the Mn(2+) and Ca(2+) ions normally present in concanavalin A are removed, the protein becomes incapable of binding saccharides. To explore the structural differences between the native and demetallized forms and their effects on the saccharide-binding properties of the protein, we have refined...

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Bibliographic Details
Main Authors: Reeke, George N., Becker, Joseph W., Edelman, Gerald M.
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC392537/
https://ncbi.nlm.nih.gov/pubmed/276870
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