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Reduced VDAC1 Protects Against Alzheimer’s Disease, Mitochondria and Synaptic Deficiencies

The objective of this study was to elucidate the effect of VDAC1 on Alzheimer’s disease (AD)-related genes, mitochondrial activity, and synaptic viability. Recent knockout studies of VDAC1 revealed that homozygote VDAC1 knockout (VDAC1−/−) mice exhibited disrupted learning and synaptic plasticity, a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Manczak, Maria, Sheiko, Tatiana, Craigen, William J., Reddy, P. Hemachandra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925364/
https://ncbi.nlm.nih.gov/pubmed/23948905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-130761
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