Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences.

Exposure of HeLa cells to Na butyrate leads to an accumulation of multiacetylated forms of histones H3 and H4. Our studies of histone acetylation in HeLa S-3 cells show that 7 mM butyrate suppresses the deacetylation of histones without influencing the rate of radioactive acetate incorporation. An a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vidali, G, Boffa, L C, Bradbury, E M, Allfrey, V G
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392527/
https://ncbi.nlm.nih.gov/pubmed/276864
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados