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Heterochromatin protein 1 forms distinct complexes to direct histone deacetylation and DNA methylation

DNA methylation, methylation of histone H3 at Lys9 (H3K9me3) and hypoacetylated histones are common molecular features of heterochromatin. Important details of their functions and inter-relationships remain unclear, however. In Neurospora crassa, H3K9me3 directs DNA methylation through a complex con...

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Détails bibliographiques
Publié dans:Nat Struct Mol Biol
Auteurs principaux: Honda, Shinji, Lewis, Zachary A., Shimada, Kenji, Fischle, Wolfgang, Sack, Ragna, Selker, Eric U.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957970/
https://ncbi.nlm.nih.gov/pubmed/22504884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2274
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