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β-catenin-mediated inhibition of cross-priming: A new mechanism for tumors to evade immunosurveillance
Cross-priming plays a major role in generating CD8(+) T cell-dependent antitumor immunity through cross-presentation. However, the cross-presentation of tumor-associated antigens by dendritic cells often promotes tolerance rather than CD8(+) T-cell immunity. We have now identified a β-catenin-depend...
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Главные авторы: | , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Landes Bioscience
2013
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925153/ https://ncbi.nlm.nih.gov/pubmed/24567866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26920 |
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