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Understanding telomere diseases through analysis of disease-specific iPS cells
A unique characteristic of tissue stem cells is the ability to self-renew, a process that enables the life-long maintenance of many organs. Stem cell self-renewal is dependent in part on the synthesis of telomere repeats by the enzyme telomerase. Defects in telomerase and in genes in the telomere ma...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925063/ https://ncbi.nlm.nih.gov/pubmed/23993228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2013.07.006 |
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