Telomere shortening and loss of self-renewal in dyskeratosis congenita iPS cells

The differentiation of patient-derived induced pluripotent stem cells (iPSCs) to committed fates such as neurons, muscle and liver is a powerful approach for understanding key parameters of human development and disease(1–6). Whether undifferentiated iPSCs themselves can be used to probe disease mec...

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Detalhes bibliográficos
Main Authors: Batista, Luis F.Z., Pech, Matthew F., Zhong, Franklin L., Nguyen, Ha Nam, Xie, Kathleen T., Zaug, Arthur J., Crary, Sharon M., Choi, Jinkuk, Sebastiano, Vittorio, Cherry, Athena, Giri, Neelam, Wernig, Marius, Alter, Blanche P., Cech, Thomas R., Savage, Sharon A., Reijo Pera, Renee A., Artandi, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155806/
https://ncbi.nlm.nih.gov/pubmed/21602826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10084
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