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Peripheral interactions between cannabinoid and opioid systems contribute to the antinociceptive effect of crotalphine

BACKGROUND AND PURPOSE: Crotalphine is an antinociceptive peptide that, despite its opioid-like activity, does not induce some of the characteristic side effects of opioids, and its amino acid sequence has no homology to any known opioid peptide. Here, we evaluated the involvement of the peripheral...

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Detalhes bibliográficos
Main Authors: Machado, F C, Zambelli, V O, Fernandes, A C O, Heimann, A S, Cury, Y, Picolo, G
Formato: Artigo
Idioma:Inglês
Publicado em: John wiley & Sons Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925035/
https://ncbi.nlm.nih.gov/pubmed/24460677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12488
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