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Regulation of cholesterol biosynthesis in HeLa S3G cells by serum lipoproteins: Dexamethasone-mediated interference with suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase

Depression of the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase [mevalonate:NADP(+) oxidoreductase (CoA-acylating); EC 1.1.1.34] was elicited by the removal of serum from the growth medium of HeLa S3G cells with a concomitant expected increase in cellular sterol biosynthesis;...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Cavenee, Webster K., Johnston, Dean, Melnykovych, George
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/209449/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.5.2103
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