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A synthetic biology approach to the development of transcriptional regulatory models and custom enhancer design(,)

Synthetic biology offers novel opportunities for elucidating transcriptional regulatory mechanisms and enhancer logic. Complex cis-regulatory sequences—like the ones driving expression of the Drosophila even-skipped gene—have proven difficult to design from existing knowledge, presumably due to the...

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Autores principales: Martinez, Carlos A., Barr, Kenneth, Kim, Ah-Ram, Reinitz, John
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924567/
https://ncbi.nlm.nih.gov/pubmed/23732772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.05.014
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