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Promotion of monolayer formation in cultured whole pancreatic islets by 3-isobutyl-1-methylxanthine.

Normal adult rat islets usually remained intact and encapsulated, even after many days in culture. In contrast, islets cultured in the presence of the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (0.1 mM) attached more readily to the surface of plastic culture dishes and almost uniformly...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ohgawara, H, Carroll, R, Hofmann, C, Takahashi, C, Kikuchi, M, Labrecque, A, Hirata, Y, Steiner, D F
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1978
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392448/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/347449/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.4.1897
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