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Promotion of monolayer formation in cultured whole pancreatic islets by 3-isobutyl-1-methylxanthine.

Normal adult rat islets usually remained intact and encapsulated, even after many days in culture. In contrast, islets cultured in the presence of the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (0.1 mM) attached more readily to the surface of plastic culture dishes and almost uniformly...

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Detalhes bibliográficos
Main Authors: Ohgawara, H, Carroll, R, Hofmann, C, Takahashi, C, Kikuchi, M, Labrecque, A, Hirata, Y, Steiner, D F
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392448/
https://ncbi.nlm.nih.gov/pubmed/347449
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