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Proteases induce secretion of collagenase and plasminogen activator by fibroblasts

We have observed that treatment of rabbit synovial fibroblasts with proteolytic enzymes can induce secretion of collagenase (EC 3.4.24.7) and plasminogen activator (EC 3.4.21.-). Cells treated for 2-24 hr with plasmin, trypsin, chymotrypsin, pancreatic elastase, papain, bromelain, thermolysin, or α-...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Werb, Zena, Aggeler, Judith
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/205872/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.4.1839
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