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Proteases induce secretion of collagenase and plasminogen activator by fibroblasts

We have observed that treatment of rabbit synovial fibroblasts with proteolytic enzymes can induce secretion of collagenase (EC 3.4.24.7) and plasminogen activator (EC 3.4.21.-). Cells treated for 2-24 hr with plasmin, trypsin, chymotrypsin, pancreatic elastase, papain, bromelain, thermolysin, or α-...

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Main Authors: Werb, Zena, Aggeler, Judith
格式: Artigo
語言:Inglês
出版: 1978
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC392436/
https://ncbi.nlm.nih.gov/pubmed/205872
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