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Proteases induce secretion of collagenase and plasminogen activator by fibroblasts

We have observed that treatment of rabbit synovial fibroblasts with proteolytic enzymes can induce secretion of collagenase (EC 3.4.24.7) and plasminogen activator (EC 3.4.21.-). Cells treated for 2-24 hr with plasmin, trypsin, chymotrypsin, pancreatic elastase, papain, bromelain, thermolysin, or α-...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Werb, Zena, Aggeler, Judith
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/205872/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.4.1839
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