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Mutational analysis of the rotavirus NSP4 enterotoxic domain that binds to caveolin-1

BACKGROUND: Rotavirus (RV) nonstructural protein 4 (NSP4) is the first described viral enterotoxin, which induces early secretory diarrhea in neonatal rodents. Our previous data show a direct interaction between RV NSP4 and the structural protein of caveolae, caveolin-1 (cav-1), in yeast and mammali...

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Detalhes bibliográficos
Main Authors: Ball, Judith M, Schroeder, Megan E, Williams, Cecelia V, Schroeder, Friedhelm, Parr, Rebecca D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924327/
https://ncbi.nlm.nih.gov/pubmed/24220211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-336
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