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Elucidation of the Rotavirus NSP4-Caveolin-1 and -Cholesterol Interactions Using Synthetic Peptides

Rotavirus (RV) NSP4, the first described viral enterotoxin, is a multifunctional glycoprotein that contributes to viral pathogenesis, morphogenesis, and replication. NSP4 binds both termini of caveolin-1 and is isolated from caveolae fractions that are rich in anionic phospholipids and cholesterol....

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Autors principals: Schroeder, Megan E., Hostetler, Heather A., Schroeder, Friedhelm, Ball, Judith M.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303745/
https://ncbi.nlm.nih.gov/pubmed/22500212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/575180
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