Generation and Characterization of Function-blocking Anti-ectodysplasin A (EDA) Monoclonal Antibodies That Induce Ectodermal Dysplasia

Development of ectodermal appendages, such as hair, teeth, sweat glands, sebaceous glands, and mammary glands, requires the action of the TNF family ligand ectodysplasin A (EDA). Mutations of the X-linked EDA gene cause reduction or absence of many ectodermal appendages and have been identified as a...

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Bibliographische Detailangaben
Hauptverfasser: Kowalczyk-Quintas, Christine, Willen, Laure, Dang, Anh Thu, Sarrasin, Heidi, Tardivel, Aubry, Hermes, Katharina, Schneider, Holm, Gaide, Olivier, Donzé, Olivier, Kirby, Neil, Headon, Denis J., Schneider, Pascal
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924290/
https://ncbi.nlm.nih.gov/pubmed/24391090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.535740
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