Prenatal Treatment of X-Linked Hypohidrotic Ectodermal Dysplasia Using Recombinant Ectodysplasin in a Canine Model

X-linked hypohidrotic ectodermal dysplasia (XLHED) is caused by defects in the EDA gene that inactivate the function of ectodysplasin A1 (EDA1). This leads to abnormal development of eccrine glands, hair follicles, and teeth, and to frequent respiratory infections. Previous studies in the naturally...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pharmacol Exp Ther
Egile Nagusiak: Margolis, Carol A., Schneider, Pascal, Huttner, Kenneth, Kirby, Neil, Houser, Timothy P., Wildman, Lee, Grove, Gary L., Schneider, Holm, Casal, Margret L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2019
Gaiak:
Special Issue on Drug Delivery Technologies
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812859/
https://ncbi.nlm.nih.gov/pubmed/31000577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.256040
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