α6 Integrin Transactivates Insulin-like Growth Factor Receptor-1 (IGF-1R) to Regulate Caspase-3-mediated Lens Epithelial Cell Differentiation Initiation

The canonical mitochondrial death pathway was first discovered for its role in signaling apoptosis. It has since been found to have a requisite function in differentiation initiation in many cell types including the lens through low level activation of the caspase-3 protease. The ability of this pat...

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Detalhes bibliográficos
Main Authors: Basu, Subhasree, Rajakaruna, Suren, De Arcangelis, Adèle, Zhang, Liping, Georges-Labouesse, Elisabeth, Menko, A. Sue
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924254/
https://ncbi.nlm.nih.gov/pubmed/24381169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515254
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