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Insulin-like Growth Factor Receptor-1 and Nuclear Factor κB Are Crucial Survival Signals That Regulate Caspase-3-mediated Lens Epithelial Cell Differentiation Initiation

It is now known that the function of the caspase family of proteases is not restricted to effectors of programmed cell death. For example, there is a significant non-apoptotic role for caspase-3 in cell differentiation. Our own studies in the developing lens show that caspase-3 is activated downstre...

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Detalhes bibliográficos
Main Authors: Basu, Subhasree, Rajakaruna, Suren, Menko, A. Sue
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381865/
https://ncbi.nlm.nih.gov/pubmed/22275359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341586
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