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Regulation of adenylate cyclase activity mediated by muscarinic acetylcholine receptors.

Carbachol, an activator of muscarinic acetylcholine receptors of NG108-15 hybrid cells, inhibits adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] rapidly and reversibly and slowly evokes a 200-300% increase in adenylate cyclase activity over a period of 24-30 hr. Both the inhibiti...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nathanson, N M, Klein, W L, Nirenberg, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392425/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/205870/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.4.1788
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