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Regulation of adenylate cyclase activity mediated by muscarinic acetylcholine receptors.

Carbachol, an activator of muscarinic acetylcholine receptors of NG108-15 hybrid cells, inhibits adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] rapidly and reversibly and slowly evokes a 200-300% increase in adenylate cyclase activity over a period of 24-30 hr. Both the inhibiti...

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Bibliografiske detaljer
Main Authors: Nathanson, N M, Klein, W L, Nirenberg, M
Format: Artigo
Sprog:Inglês
Udgivet: 1978
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC392425/
https://ncbi.nlm.nih.gov/pubmed/205870
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