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Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division

Human cell nuclei are functionally organized into structurally stable yet dynamic bodies whose cell cycle inheritance is poorly understood. Here, we investigate the biogenesis and propagation of nucleoli, sites of ribosome biogenesis and key regulators of cellular growth. Nucleolar and cell cycles a...

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Detalhes bibliográficos
Main Authors: Grob, Alice, Colleran, Christine, McStay, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923965/
https://ncbi.nlm.nih.gov/pubmed/24449107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.234591.113
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