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NORs on human acrocentric chromosome p-arms are active by default and can associate with nucleoli independently of rDNA

Nucleoli, the sites of ribosome biogenesis and the largest structures in human nuclei, form around nucleolar organizer regions (NORs) comprising ribosomal DNA (rDNA) arrays. NORs are located on the p-arms of the five human acrocentric chromosomes. Defining the rules of engagement between these p-arm...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: van Sluis, Marjolein, van Vuuren, Chelly, Mangan, Hazel, McStay, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229746/
https://ncbi.nlm.nih.gov/pubmed/32332163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001812117
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