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Ampelopsin Induces Cell Growth Inhibition and Apoptosis in Breast Cancer Cells through ROS Generation and Endoplasmic Reticulum Stress Pathway

Ampelopsin (AMP), a major bioactive constituent of Ampelopsis grossedentata, exerts a number of biological effects. In this study, we investigated its anti-cancer activity in human breast cancer cell lines, and explored the underlying mechanism of this action. Our results showed that treatment with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Yong, Shu, Furong, Liang, Xinyu, Chang, Hui, Shi, Linying, Peng, Xiaoli, Zhu, Jundong, Mi, Mantian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923868/
https://ncbi.nlm.nih.gov/pubmed/24551210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089021
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