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Increased levels of palmitoylethanolamide and other bioactive lipid mediators and enhanced local mast cell proliferation in canine atopic dermatitis

BACKGROUND: Despite the precise pathogenesis of atopic dermatitis (AD) is unknown, an immune dysregulation that causes Th2-predominant inflammation and an intrinsic defect in skin barrier function are currently the two major hypotheses, according to the so-called outside-inside-outside model. Mast c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Abramo, Francesca, Campora, Luca, Albanese, Francesco, della Valle, Maria Federica, Cristino, Luigia, Petrosino, Stefania, Di Marzo, Vincenzo, Miragliotta, Vincenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923739/
https://ncbi.nlm.nih.gov/pubmed/24423192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-10-21
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