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C6 knock-out Mice Are Protected from Thrombophilia Mediated by Antiphospholipid Antibodies
BACKGROUND: Complement activation plays a role in pathogenesis of the Antiphospholipid Syndrome (APS), but the involvement of the C5b-9 membrane attack complex (MAC) is unknown. Here we studied the effects of human polyclonal antiphospholipid (aPL) antibodies on thrombosis and tissue factor (TF) up-...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3923322/ https://ncbi.nlm.nih.gov/pubmed/22933620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203312458839 |
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