Keratin 9 Is Required for the Structural Integrity and Terminal Differentiation of the Palmoplantar Epidermis

Keratin 9 (K9) is a type I intermediate filament protein whose expression is confined to the suprabasal layers of the palmoplantar epidermis. Although mutations in the K9 gene are known to cause epidermolytic palmoplantar keratoderma, a rare dominant-negative skin disorder, its functional significan...

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Detalhes bibliográficos
Main Authors: Fu, Dun Jack, Thomson, Calum, Lunny, Declan P, Dopping-Hepenstal, Patricia J, McGrath, John A, Smith, Frances J D, Irwin McLean, W H, Pedrioli, Deena M Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923277/
https://ncbi.nlm.nih.gov/pubmed/23962810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.356
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