New function for Escherichia coli xanthosine phophorylase (xapA): genetic and biochemical evidences on its participation in NAD(+) salvage from nicotinamide

BACKGROUND: In an effort to reconstitute the NAD(+) synthetic pathway in Escherichia coli (E. coli), we produced a set of gene knockout mutants with deficiencies in previously well-defined NAD(+)de novo and salvage pathways. Unexpectedly, the mutant deficient in NAD(+)de novo and salvage pathway I c...

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Hlavní autoři: Dong, Wei-Ren, Sun, Cen-Cen, Zhu, Guan, Hu, Shi-Hua, Xiang, Li-Xin, Shao, Jian-Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923242/
https://ncbi.nlm.nih.gov/pubmed/24506841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-14-29
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