A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD(+) salvage pathway in the nucleus

All cells require sustained intracellular energy flux, which is driven by redox chemistry at the subcellular level. NAD(+), its phosphorylated variant NAD(P)(+), and its reduced forms NAD(P)/NAD(P)H are all redox cofactors with key roles in energy metabolism and are substrates for several NAD-consum...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Grolla, Ambra A., Miggiano, Riccardo, Di Marino, Daniele, Bianchi, Michele, Gori, Alessandro, Orsomando, Giuseppe, Gaudino, Federica, Galli, Ubaldina, Del Grosso, Erika, Mazzola, Francesca, Angeletti, Carlo, Guarneri, Martina, Torretta, Simone, Calabrò, Marta, Boumya, Sara, Fan, Xiaorui, Colombo, Giorgia, Travelli, Cristina, Rocchio, Francesca, Aronica, Eleonora, Wohlschlegel, James A., Deaglio, Silvia, Rizzi, Menico, Genazzani, Armando A., Garavaglia, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076215/
https://ncbi.nlm.nih.gov/pubmed/31988240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010571
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