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Simple methods for the 3′ biotinylation of RNA

Biotinylation of RNA allows its tight coupling to streptavidin and is thus useful for many types of experiments, e.g., pull-downs. Here we describe three simple techniques for biotinylating the 3′ ends of RNA molecules generated by chemical or enzymatic synthesis. First, extension with either the Sc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Moritz, Bodo, Wahle, Elmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923135/
https://ncbi.nlm.nih.gov/pubmed/24448448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.042986.113
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