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Smaug assembles an ATP-dependent stable complex repressing nanos mRNA translation at multiple levels

The nanos (nos) mRNA encodes the posterior determinant of the Drosophila embryo. Translation of the RNA is repressed throughout most of the embryo by the protein Smaug binding to Smaug recognition elements (SREs) in the 3′ UTR. Translation is locally activated at the posterior pole by Oskar. This pa...

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Bibliographic Details
Main Authors: Jeske, Mandy, Moritz, Bodo, Anders, Alexander, Wahle, Elmar
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020108/
https://ncbi.nlm.nih.gov/pubmed/21081899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.283
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