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Smaug assembles an ATP-dependent stable complex repressing nanos mRNA translation at multiple levels

The nanos (nos) mRNA encodes the posterior determinant of the Drosophila embryo. Translation of the RNA is repressed throughout most of the embryo by the protein Smaug binding to Smaug recognition elements (SREs) in the 3′ UTR. Translation is locally activated at the posterior pole by Oskar. This pa...

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Bibliografische gegevens
Hoofdauteurs: Jeske, Mandy, Moritz, Bodo, Anders, Alexander, Wahle, Elmar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020108/
https://ncbi.nlm.nih.gov/pubmed/21081899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.283
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