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High Glucose Induces Podocyte Injury via Enhanced (Pro)renin Receptor-Wnt-β-Catenin-Snail Signaling Pathway

(Pro)renin receptor (PRR) expression is upregulated in diabetes. We hypothesized that PRR contributes to podocyte injury via activation of Wnt-β-catenin-snail signaling pathway. Mouse podocytes were cultured in normal (5 mM) or high (25 mM) D-glucose for 3 days. Compared to normal glucose, high gluc...

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Detalhes bibliográficos
Main Authors: Li, Caixia, Siragy, Helmy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923071/
https://ncbi.nlm.nih.gov/pubmed/24533170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089233
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