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Tertiary structure prediction and identification of druggable pocket in the cancer biomarker – Osteopontin-c

BACKGROUND: Osteopontin (Eta, secreted sialoprotein 1, opn) is secreted from different cell types including cancer cells. Three splice variant forms namely osteopontin-a, osteopontin-b and osteopontin-c have been identified. The main astonishing feature is that osteopontin-c is found to be elevated...

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Detalhes bibliográficos
Main Authors: Sivakumar, Subramaniam, Niranjali Devaraj, Sivasitambaram
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922830/
https://ncbi.nlm.nih.gov/pubmed/24401206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2251-6581-13-13
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