Human interleukin 2 can promote the growth and differentiation of single hapten-specific B cells in the presence of specific antigen.

B lymphocytes specifically reactive to the hapten fluorescein (FLU) were prepared from normal adult murine spleen by the hapten-gelatin affinity procedure. They were placed in 10 microliter of microcultures singly or in small numbers in the absence of any feeder, filler, or accessory cell. The "...

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Bibliographic Details
Main Authors: Pike, B L, Raubitschek, A, Nossal, G J
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC392264/
https://ncbi.nlm.nih.gov/pubmed/6334854
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