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Human interleukin 2 can promote the growth and differentiation of single hapten-specific B cells in the presence of specific antigen.

B lymphocytes specifically reactive to the hapten fluorescein (FLU) were prepared from normal adult murine spleen by the hapten-gelatin affinity procedure. They were placed in 10 microliter of microcultures singly or in small numbers in the absence of any feeder, filler, or accessory cell. The "T ce...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Pike, B L, Raubitschek, A, Nossal, G J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392264/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6334854/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.24.7917
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