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Absence of RNase H allows replication of pBR322 in Escherichia coli mutants lacking DNA polymerase I.
rnh (formerly termed sdrA) mutants of Escherichia coli K-12, capable of continuous DNA replication in the absence of protein synthesis (stable DNA replication), are devoid of ribonuclease H (RNase H, EC 3.1.26.4) activity. Plasmid pBR322 was found to replicate in rnh mutants in the absence of DNA po...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6096862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.24.7845 |
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