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Absence of RNase H allows replication of pBR322 in Escherichia coli mutants lacking DNA polymerase I.

rnh (formerly termed sdrA) mutants of Escherichia coli K-12, capable of continuous DNA replication in the absence of protein synthesis (stable DNA replication), are devoid of ribonuclease H (RNase H, EC 3.1.26.4) activity. Plasmid pBR322 was found to replicate in rnh mutants in the absence of DNA po...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autor Principal: Kogoma, T
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1984
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6096862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.24.7845
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