Polycyclic aromatic hydrocarbon mutagenesis of human epidermal keratinocytes in culture.
We have developed a culture system for detecting and isolating rare hypoxanthine phosphoribosyltransferase-deficient mutants of human epidermal keratinocytes. A thioguanine-resistant variant, 3T3M1, of the Swiss mouse fibroblast line 3T3 was used as a feeder layer to support clonal growth of mutant...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1984
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6440145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.24.7802 |
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