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Neither T-helper type 2 nor Foxp3(+) regulatory T cells are necessary for therapeutic benefit of atorvastatin in treatment of central nervous system autoimmunity

Oral atorvastatin has prevented or reversed paralysis in the multiple sclerosis (MS) model experimental autoimmune encephalomyelitis (EAE), and reduced development of new MS lesions in clinical trials. Besides inhibiting development of encephalitogenic T cells, atorvastatin treatment of EAE has been...

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Bibliografische gegevens
Hoofdauteurs: Weber, Martin S, Prod’homme, Thomas, Youssef, Sawsan, Dunn, Shannon E, Steinman, Lawrence, Zamvil, Scott S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922392/
https://ncbi.nlm.nih.gov/pubmed/24498870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-29
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