Adaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stress

BACKGROUND: Like normal hematopoietic stem cells, leukemia cells proliferate in bone marrow, where oxygen supply is limited. However, the growth and energy metabolism of leukemia cells under hypoxia have not been well understood. Although it has been known that reactive oxygen species (ROS) is gener...

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Detalhes bibliográficos
Main Authors: Goto, Mineaki, Miwa, Hiroshi, Suganuma, Kazuto, Tsunekawa-Imai, Norikazu, Shikami, Masato, Mizutani, Motonori, Mizuno, Shohei, Hanamura, Ichiro, Nitta, Masakazu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922169/
https://ncbi.nlm.nih.gov/pubmed/24506813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-76
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