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Hypersensitive termination of the hypoxic response by a disordered protein switch
The cellular response to hypoxia is critical for cell survival and is fine-tuned to allow cells to recover from hypoxic stress and adapt to heterogeneous or fluctuating oxygen levels(1,2). The hypoxic response is mediated by the α subunit of the transcription factor HIF-1 (HIF-1α)(3), which interact...
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| Publicado no: | Nature |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5375031/ https://ncbi.nlm.nih.gov/pubmed/28273070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21705 |
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