Novel mutations in penicillin-binding protein genes in clinical Staphylococcus aureus isolates that are methicillin resistant on susceptibility testing, but lack the mec gene

OBJECTIVES: Methicillin-resistant Staphylococcus aureus (MRSA) is an important global health problem. MRSA resistance to β-lactam antibiotics is mediated by the mecA or mecC genes, which encode an alternative penicillin-binding protein (PBP) 2a that has a low affinity to β-lactam antibiotics. Detect...

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Main Authors: Ba, Xiaoliang, Harrison, Ewan M., Edwards, Giles F., Holden, Matthew T. G., Larsen, Anders Rhod, Petersen, Andreas, Skov, Robert L., Peacock, Sharon J., Parkhill, Julian, Paterson, Gavin K., Holmes, Mark A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2014
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Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922151/
https://ncbi.nlm.nih.gov/pubmed/24216768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt418
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