Old Drugs To Treat Resistant Bugs: Methicillin-Resistant Staphylococcus aureus Isolates with mecC Are Susceptible to a Combination of Penicillin and Clavulanic Acid

β-Lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA) is mediated by the expression of an alternative penicillin-binding protein 2a (PBP2a) (encoded by mecA) with a low affinity for β-lactam antibiotics. Recently, a novel variant of mecA, known as mecC, was identified in MRSA iso...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ba, Xiaoliang, Harrison, Ewan M., Lovering, Andrew L., Gleadall, Nicholas, Zadoks, Ruth, Parkhill, Julian, Peacock, Sharon J., Holden, Matthew T. G., Paterson, Gavin K., Holmes, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649192/
https://ncbi.nlm.nih.gov/pubmed/26392513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01469-15
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