Generation and Characterization of Recombinant Influenza A(H1N1) Viruses Resistant to Neuraminidase Inhibitors

OBJECTIVES: To examine the effect of neuraminidase (NA) mutations on the NA inhibitor (NAI) resistance phenotype, the recombinant influenza A/Chungbuk/4448/2008(H1N1) virus isolated in South Korea during the 2008–2009 season was generated by reverse genetics. METHODS: Site-directed mutagenesis was i...

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Autores principales: Choi, WooYoung, Shin, Jin-Young, Jeong, Hwan-Eui, Jeong, Mi-Jin, Kim, Su-Jin, Lee, Joo-Yeon, Kang, Chun
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922101/
https://ncbi.nlm.nih.gov/pubmed/24524021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrp.2013.10.005
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