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The differential interferon responses of two strains of Stat1-deficient mice do not alter susceptibility to HSV-1 and VSV in vivo

Stat1 is a pivotal transcription factor for generation of the interferon (IFN)-dependent antiviral response. Two Stat1 knockout mouse lines have been previously generated, one deleted the N-terminal domain (DNTD) and one in the DNA-binding domain (DDBD). These widely-used strains are assumed interch...

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Detalhes bibliográficos
Main Authors: Katzenell, Sarah, Chen, Yufei, Parker, Zachary M., Leib, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922067/
https://ncbi.nlm.nih.gov/pubmed/24503098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.12.015
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