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Phenotype and function of protective, CD4-independent CD8 T cell memory

While the need for CD4 T cells in the generation of CD8 T cell memory has been well documented, the mechanism underlying their requirement remains unknown. Here, we detail an immunization method capable of generating CD8 memory T cells that are indifferent to CD4 T cell help. Using a subunit vaccina...

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Detalhes bibliográficos
Main Authors: Edwards, Lindsay E., Haluszczak, Catherine, Kedl, Ross M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922058/
https://ncbi.nlm.nih.gov/pubmed/22948808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-012-8356-9
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